Pastor Lonnie Hardy's sermon "Cut It Off Now!" delves into the concept of woe from the book of Matthew, highlighting the need for childlike faith and humility to achieve greatness in the kingdom of heaven. He condemns abusing children and warns against using worldly tactics for advancement. The sermon also addresses the problematic influences of the entertainment industry and advocates for repentance and standing against worldly principles. Ultimately, Pastor Hardy encourages repentance, service, and alignment with God's principles as the keys to success in the kingdom.